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Revisiting Celexa vs Lexapro: effect of r-isomer

Posted by Mtom on July 10, 2018, at 9:38:17

In reply to Re: More research: Celexa versus Lexapro, posted by Tony P on May 19, 2018, at 21:59:46

Earlier posts discussed whether the r-isomer in Celexa is inactive, as most believe, or whether, according to a couple of papers, it might actually interfere with the antidepressant activity of the s-isomer (Celexa has both, Lexapro only the s).

It is commonly stated that Lexapro has twice the AD activity of Celexa per dosage because it contains only the active isomer.

However, if in fact the r-isomer in Celexa does interfere with the AD activity of the s-isomer, it would seem to me that Lexapro would then be "more" than twice as potent per dosage?
Thoughts? Any more research?

Also, how small are the Lexapro pills for cutting? I take very small doses due to hypersensitivity, and I find that small pills tend to crumble, even with a pill cutter or razor knife.





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