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Re: What is your opinion on P. K. Gillman + his views? » Hordak

Posted by linkadge on July 7, 2018, at 17:25:58

In reply to Re: What is your opinion on P. K. Gillman + his views? » linkadge, posted by Hordak on July 7, 2018, at 15:58:24

My hunch is that because his focus is on MAO and reuptake inhibiting mechanisms, he doesn't see mirtazapine as a 'true' antidepressant.

However, there is quite a bit of literature suggesting that 5-ht2 antagonists and alpha-2 antagonists have antidepressant effects. For example, 5-ht2c antagonists and alpha-2 antagonists have independent neurotrophic properties.

To be honest, I wish that mirtazapine was my first antidepressant. I honestly think I would have recovered a bit better. I think all the reuptake stuff altered my brain in adolecence.

Linkadge


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