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Paxil not as good as St Johns Wort in this study

Posted by bleauberry on June 27, 2018, at 6:38:14

My personal experience with SJW is that when/if it kicks in - for me that was in the 3-5 week range - the anti-depressive effect didn't have the numbing effect of SSRIs, but was more natural and open with a general feeling of contentment and re-engagement in life.

The other thing I have learned from personal experience (years ago) is that you can generate some serious Herxheimer reactions with it. A Herx (for short) is a die-off reaction of pathogenic microbes that causes a systemic inflammation response resulting in depression, anxiety, pain and fatigue. This is maybe one of the most accurate ways to diagnose a hidden case of Lyme - see if you can generate a Herx - because a healthy person won't be able to - a Lyme person will generate a Herx very easily.

Studies indicate that SJW has enough power as an antibiotic, anti fungal, and especially antiviral, to deal with prescription-resistant strains. I didn't know years ago it was a Herx - I thought SJW was just making me worse - but then when it kicked in it was pretty amazing. No prescription ever did that in all the years that followed. Wouldn't you know it, a psychiatrist got pissed at me for using SJW, actually yelled at me and lectured me, forced me to stop SJW, not happy I was doing much better, and then I crashed badly after that, and crashed even worse when that doc put me on Serzone instead. What a joke. Sick joke.

I'm thinking of maybe re-visiting SJW in terms of Lyme rather than in terms of mood. It is a powerful anti-microbial, anti-inflammatory, anti-pain, anti-cancer, neuroprotective, with mood lifting and anti-anxiety properties.

Efficacy of Hypericum extract WS() 5570 compared with paroxetine in patients with a moderate major depressive episode - a subgroup analysis.

Seifritz E1, Hatzinger M2, Holsboer-Trachsler E3.
Author information
Abstract
OBJECTIVES:
efficacy and tolerability of WS() 5570 for the treatment of acute mild-to-moderate depression, has been demonstrated in various studies. Here, we present a subgroup analysis of a double blind, randomised trial to compare the therapeutic efficacy of WS() 5570 with paroxetine in patients suffering from a major depressive episode with moderate symptom intensity.
METHODS:
moderate depression was defined by a baseline Hamilton Depression Rating Scale (HAM-D) total score between 22 and 25. Patients received, after a single blind placebo run-in phase of 3-7 d, either 3  300 mg/d WS() 5570 or 20 mg/d paroxetine for six weeks. The change of the HAM-D total score was used to describe the efficacy of WS() 5570 compared with paroxetine in the subgroup of patients with moderate depression.
RESULTS:
the reductions of the HAM-D total score were significantly more pronounced in patients treated with 3  300 mg/d WS() 5570 compared to 20 mg/d paroxetine.
CONCLUSIONS:
patients treated with WS() 5570 not only showed a reduction in depression severity score but also yielded greater response and remission rates compared with patients treated with paroxetine. Keypoints Various studies showed the efficacy and tolerability of WS() 5570 for the treatment of acute mild-to-moderate depression. Beneficial effects of WS() 5570 have been also shown in patients with moderate-to-severe depression. In this study reductions of the HAM-D total score were significantly more pronounced in patients with moderate depression treated with WS() 5570 compared with paroxetine. Patients treated with WS() 5570 not only showed a reduction in depression severity score but also yielded greater response and remission rates compared with patients treated with paroxetine.


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Psycho-Babble Medication | Framed

poster:bleauberry thread:1099311
URL: http://www.dr-bob.org/babble/20180521/msgs/1099311.html