Psycho-Babble Medication | about biological treatments | Framed
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any drugs with strong NRI action ?

Posted by TriedEveryMedication on June 25, 2018, at 14:59:48

my adhd-pi seems to respond to NRIs, especially desipramine.

I've tried atomoxetine which I've seen marketed as a "safer desipramine", but it just doesn't work as well.

the Ki for atomoextine for NET is 5 and for desipramine is like 0.2. (lower the constant, the greater the affinity)

reboxetine isn't available in the US and its binding profile with NET is 13, weaker than atomoxetine.

I guess Protriptyline is an option, its Ki is 1.4. still weaker than desipramine, though.




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