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Re: Any experience with Trintellix?

Posted by PeterMartin on April 29, 2018, at 1:46:18

In reply to Re: Any experience with Trintellix? PeterMartin, posted by SLS on April 28, 2018, at 15:13:02

> > Have you taken the Gavis version of Nardil?
> I don't know what version of Nardil I used last. Where would I get Gavis?

Just call the pharmacy ahead of time and ask which generic manufacturer they carry for Nardil (if they even have it in stock). Then say you need the Lupin version (sorry I should have mentioned Gavis was just bought by Lupin so it'll eventually be in called Lupin in their system if not already but same thing). From what I've read on the forum Gavis intended to make the coating like the original when they started making the generic. Greenstone is exactly the same as Pfizers. While people who took the original pre-2004 version of Nardil still don't think Gavis(Lupin) is as good almost all say it's stronger than Greenstone. It's finally kicked in for me after 3months (6wks on 60 and 6wks on 75).

I've never personally taken the Greenstone but I regardless of bioavailability I respond very differently to different generics. Topamx/Lamictal/Seroquel.....different brands do cause different side effects or feel stronger. In some cases (Lamictal) some generics flat out don't work for me. Greenstone seemed to be more popular originally but I think Gavis/Lupin is just as common now. Since there was a decent chance in the past you took the Pfizer/Greenstone brand if you do go back on Nardil at least keep track of the generic brand you try. If you hit a wall w/ it switch. That might be enough to give you better results.

> > Metformin has prevented major weight gain so far btw (only up 2lbs at 3months and just up to the full 2000 so hoping to maybe lose).
> That's very good news. Do you get any GI side effects?

I BM more with it which honestly is a great thing. I did seem to get pretty tired after each dose increase for a a few days to a week. It's a little difficult to gauge since I started Nardil at the same time. I've only been on 2000 for a few days now and this is the real test. If I start _losing_ weight than I'll ecstatic. Keeping Nardil wt. neutral is my main goal though.

If the met starts to fail I think my only real option is Zonegran which seems to be either great or terrible. Similar cognitive effects like Topamax but the wt loss is supposed to be great. I've also heard Topamax doesn't tend to work for wt loss if you've taken it before (which I have). I'm optimistic Metformin will help though - I'll continue to update.




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