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Re: LDN Success - Anyone? » bleauberry

Posted by SLS on April 14, 2018, at 5:57:03

In reply to Re: LDN Success - Anyone? » SLS, posted by bleauberry on April 13, 2018, at 8:31:03

Hi, Bleauberry.

I apologize. I thought I had posted a note of gratitude earlier. I guess I forgot to click on the appropriate confirm button.

Thank you for your input. I appreciate the time you take to post things.


- Scott


-----------------------------------------------------------


> I had pseudo-success with it. I have read anecdotal stories of success stories and failures.
>
> The science behind it is fascinating. I think there is a lot there that we don't know. Great potential.
>
> I took it for lyme not for depression - but at about 30 days my depression was improving - I was just too unstable at the time and couldn't hang in there. It requires time and patience. But I was relying on Vicadin once or twice a week to give me the stepping stone, parachute, or life preserver, to get me to to the next day or three. Vicadin obviously messed up the whole LDN approach. I was just too unstable at the time to manage it.
>
> I recall the manner in which my depression was improving at that time. It was different than antidepressants. It was more of a return-to-hobbies kind of a thing, return to interest-in-things, interest in talking with people, comfortable in a crowd, a lessened feeling of dread, a greater feeling of peace. There was none of the numbing effect at all. It felt more natural than chemical.
>
> I remember I was so sensitive I did about half of the LDN dose and even that seemed a bit much!
>
> Personally I think there is good potential with this treatment for a wide variety of diseases and syndromes. I think because it is unconventional and takes time to work that it doesn't get the fair attention it should get.
>
> The cost of getting a few months supply from a compounding pharmacy isn't too expensive so I think anyone looking to try a different chapter should take a look at it.
>
> I have a hypothesis of how it works from my perspective of infection/psychiatry:
>
> Blocking the opioid receptors briefly during sleep causes the feedback loops to release more natural opioid substances. Over weeks the total concentration of natural opioids accumulates and rises.
>
> Meanwhile, as assumed infection is sending debris to the brain mood receptors - poop, pee, enzymes, dead body parts - toxins are hitting the opioid receptors and dopamine receptors. According to some studies I saw at PubMed, these infection by-product toxins have strong affinity for our brain receptors. They crowd out our feel-good chemicals. As LDN increases natural opioids, the increased levels compete with the debris and kick some of that debris out. The patient feels better.
>
> I came up with this hypothesis because of my response to Vicadin. When I was at my worst during active infection or during Herx (pretty much the same thing either way), I took 1 1/2 Vicadin pills for relief and they totally cured me for a few hours. My reasoning was that the affinity of Vicadin for mood receptors is stronger than the affinity of infectious debris or endotoxins. As Vicadin kicked the debris out, I felt better fast.
>
> But Vicadin makes you feel good anyway, right? Well, no, not with me. I have taken Vicadin when I did not have much of an active infection or Herx. It feels like a different drug. If I don't need it, it makes me feel depressed, slow, groggy, and I can't wait for it to wear off! But when infected o r in a Herx, the opposite reaction happens, and it feels good instead. Actually 'normal' is a better word than 'good'. Vicadin made me feel normal - not high, not drugged.
>
> I think LDN does the same thing. But slower and more enduring.
>
> LDN impacts the immune system in a big way, a positive way, and helps to balance a lot of systems which are out of balance.
>
> I do not know of anyone, personally, who has taken LDN. It's just not a well known tactic. I wish it was.
>
> > Any LDN success stories for depression?
> >
> > (low-dose naltrexone)
> >
> > Thanks.
> >
> > :-)
> >
> >
> > - Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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