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Re: pharmaceutical industry and their 'reinventions'. » Hordak

Posted by SLS on April 12, 2018, at 21:59:59

In reply to Re: pharmaceutical industry and their 'reinventions'., posted by Hordak on April 12, 2018, at 10:29:52

> > like they could make new anti-depressants that work totally diffrent than others, they already have with Viibryd and serotonin modulators, instead of serotonin reptake inhibtors
>
> How the f*ck is Vilazodone totally different?
> It's an SSRI with some 5HT partial agonism...

In what ways were you disappointed by vilazodone?

The brain, psychiatric disorders, and the drugs that are used to treat them are not fully understood. New properties of old drugs are discovered often enough such that it becomes easier to understand why two people can respond so differently to the same drug.

I tried vilazodone. It worked for me for awhile. It was a very clean drug. I didn't experience side effects typical of the classic SSRIs. Different is different. For each new drug that comes to market, a certain percentage of previously TRD patients will respond to it. If drug companies want to bring new drugs to market, what's the problem? Drugs with novel antidepressant properties are being worked on right now. Hopefully, we will soon see ketamine-like drugs without dissociative or psychotomimetic effects that can be taken orally. Personally, I would like to see hydroxynorketamine (HNK) looked at.

I'm grateful for anything new that comes along that might bring me to remission. The next drug that I am scheduled to try is vortioxetine. I have no reason to be optimistic, but it is different.

I don't know what you are searching for, but I hope you find it quickly.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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