Posted by ed_uk2010 on March 25, 2018, at 17:25:52
In reply to Re: How can I block Cortisol?, posted by farshad on March 25, 2018, at 17:06:47
>If I went on zyprexa since its an antagonist on the dopamine receptors and many others, would my body evnetually upregulate them? Since I heard if you use an agonist on a receptor too much your body starts decreasing the activity and if you block something too much your body starts increasing . is that true?
Hi F,
There can be truth in that for some drugs. This can lead to unexpected effects. As an example, people who take benzodiazepines or opioids regularly can experience a reduction in effectiveness.
With antipsychotics, there is a theory that taking potent dopamine D2 receptor antagonists long term can lead to receptor upregulation. This may be a cause of tardive dyskinesia.
With olanzapine (Zyprexa) at low doses, and in younger people, tardive dyskinesia is not a high risk. The main risks are due to weight gain and associated metabolic issues.
Although I can't make any definitive suggestions for yourself because I don't know much about your medical and psychiatric problems, I can say that some people with agitated depression find small doses of olanzapine very calming, although it can be sedating initially. I'm unsure what you most want from a medication...
poster:ed_uk2010
thread:1097352
URL: http://www.dr-bob.org/babble/20180212/msgs/1097702.html