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How do SSRIs normalise the amygdala?

Posted by farshad on February 15, 2018, at 17:19:57

if people with anxiety have too much serotonin in the amygdala then how does an SSRI that increase serotonin normalise the activity in the amygdala?

Amygdala responses to fearful facial expressions were significantly greater in depressed patients compared to healthy controls. However, this response was normalised in patients receiving 7 days treatment with escitalopram. There was no significant difference in clinical depression ratings at 7 days between the escitalopram and placebo-treated patients.




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