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Re: What Drug is the best serotonin receptor antagonis

Posted by farshad on January 23, 2018, at 11:30:12

In reply to Re: What Drug is the best serotonin receptor antagonis farshad, posted by SLS on January 23, 2018, at 9:32:49

> I think I understand your rationale. It is quite sophisticated. Perhaps the whole synaptic transducing communication system is a complex set of regulators that act to approximate a value in the fashion of a thermostat with negative feedback loops.
> Would chronic blockade of 5-HT2/3 postsynaptic receptors result in their upregulation? Just curious. What about heteroreceptors?
> Effexor is one of my favorite drugs. How did you react to Effexor at dosages at or above 300 mg/day?
> - Scott

I dont know it was a long time ago since I took effexor. I took it for like 2 weeks if not less.. felt nothing.. maybe more nauseous and I felt like the type of high I imagine you would get from smoking weed.

why would chronic blockade lead to upregulation? my serotonin receptors dont get disentized anyway so it will always stay the same. I imagine for normal people it would cause upregulation.

im not an expert at all when it comes to these stuff thats why I came here to ask for help maybe someone can teach me something. I know there are serotonin receptors all over the fear regions like the amygdala so if mianserin can block the serotonin receptors it can decrease amygdala activity and reduce stress/fear.
I know what a autoreceptor is it regulates neurontransmitters so you dont get too much right? but what is a heteroreceptors?




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