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Re: Everything is good, except for depression Phillipa

Posted by SLS on November 29, 2017, at 7:14:54

In reply to Re: Everything is good, except for depression, posted by Phillipa on November 28, 2017, at 22:37:17

> It's complicated so best to google it yourself. Not sure why that was posted. But TCA are known to be not that great for the heart

Neither is untreated depression.

If desipramine brought me into remission, I would not worry about bundle-branch block unless it actually appeared early in treatment. Some doctors will take a baseline ECG and compare it to one taken after treatment is initiated. I am not very afraid of tricyclics because I have been on and off of them since 1982. It was a time when SSRIs were not yet available. I didn't have much choice. I have no statistics to offer, as they are so variable in the medical literature. Heart block seems to be a rather uncommon event in the absence of preexisting CVD. Personally, I have yet to see or hear of a case in real life when desipramine is used at therapeutic dosaages. Still, as with so many unrelated drugs used for a variety of conditions, TCAs must be used judiciously and monitored by someone who knows their side effect profiles.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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