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Re: NE strengths of Reboxetine vs Atomoxetine linkadge

Posted by MightyKondrian on October 14, 2017, at 15:16:06

In reply to Re: NE strengths of Reboxetine vs Atomoxetine, posted by linkadge on October 14, 2017, at 14:59:27

> I find that nortriptyline is more sedating than SSRIs.
>
> Mind you, it has some anti-histamine, anti-serotonin effects.
>
> The thing with NRIs is that, norepinephrine reuptake inhibition doesn't necessarily promote norepinephrine release. In fact, in the short term at least, it might decrease norepinephrine release via inhibitory feedback receptors.
>
> I find that nortriptyline helps me sleep. Although, I may have some ADHD, in which case the drug is 'calming' me by addressing ADHD symtpoms.
>
> Linkadge

Nortriptyline is anti-histaminic, you just said it. Thats not its main therapeutic effect. Its a side effect. Also its effect on your possible ADHD symptoms would fit right, being an NRI. It all adds up.
Just my calculated view ;)

Mighty Warrior


Phenelzine 120mg,Amitriptyline 100mg,Clonazepam 4mg,Bupropion 450mg,Aripiprazole 5mg,Acamprosate 2g,Clonidine 200mcg + nootropics
"If ur in full control then ur not going fast enough"-Mario Andretti


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poster:MightyKondrian thread:1095398
URL: http://www.dr-bob.org/babble/20161215/msgs/1095425.html