Psycho-Babble Medication | about biological treatments | Framed
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Re: Trintellix...Weaker SRI?

Posted by linkadge on October 8, 2017, at 7:50:32

In reply to Trintellix...Weaker SRI?, posted by phidippus on October 7, 2017, at 18:36:18

Looking in Wikipedia:

it has a ki for the serotonin transporter similar to SSRIs. However, it also has relatively strong effects on other serotonin receptors i.e. 5-ht1a.

So, perhaps the alternative mechanisms allow one to take the drug at a dose where serotonin reuptake inhibition is less prominent than with SSRIs.

I would have to look for a study which investigates the degree of serotonin transporter binding, at therapeutic doses of the drug.





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