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Re: Benedryl + Seroquel? Sheilac

Posted by SLS on August 6, 2017, at 5:54:01

In reply to Benedryl + Seroquel?, posted by Sheilac on August 2, 2017, at 18:54:59

> I've dropped my dose of Seroquel to 50mg. My muscle pain is gone and my body feels better. I hate to drop it, because I love the sleep I get with it. I'm hoping that I can slowly up it to 100mg. I'm wondering if I go slowly if I can dose back up to 100mg or even higher?

What's wrong with your sleep?

You are avoiding the Z drugs?

How is your sleep with 50 mg/day of Seroquel? The muscle pain is probably EPS. Perhaps there is another explanation that someone can offer. Either way, I personally would avoid a drug that produced that side effect at dosages that are necessary to gain a therapeutic effect.

You've tried trazodone already?

Maybe hydroxyzine?

Promethazine?

Cyproheptadine?

I would be reluctant to try full dosages of Remeron given your propensity for mania. However, 7.5-15.0 mg might work safely. Most people rave about its sleep-promoting effects.

> > Does anyone know if rapid dosing was the cause of the muscle tightness & pain?

I guess it's possible, but I wouldn't bet on it.

> Would taking Benedryl prevent the muscle tightness?

That's a good thought. I don't like the idea of masking EPS, though. It might hide the development of tardive dyskinesia. I don't know this for sure, but I think it is worth researching. I think you would be better off looking for another drug for sleep before deciding to commit yourself to Seroquel at higher dosages.

If I were in your position, I would try the slow titration of Seroquel as you suggested. You are already taking it. If this becomes problematic, I would look to try low-dosage Remeron or perhaps hydroxyzine.

Linkadge would be the right person to ask about low-dosage amitriptyline and the risk of mania. 25 mg might be okay.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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