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Re: What you think of research on long term SSRI use

Posted by linkadge on January 8, 2017, at 16:39:16

In reply to Re: What you think of research on long term SSRI use, posted by Tony P on January 6, 2017, at 16:28:48

Some people develop tolerance to antidepressants. We don't know the exact reasons. However, not everybody does develop a tolerance.

In terms of homeostasis, you are right. However, think of it this way. 'Homeostasis' is not depressed. The body wants to maintain a slightly positive mood as this is beneficial for the entire system.

My hunch, is that, if an antidepressant is making you feel better than normal, or if it is only masking the depressogenic effect of certain unresolved environmental stressors, than yes it can poop out, as your body will look to fight it off.

I know, in my life, if I haven't dealt with stressors (or toxic relationships) in my life, then eventually the depression comes back.

I have found the addition of lithium very beneficial in keeping me well for longer periods of time without relapse.

Keep in mind too, that this is a disease. Relapse can happen whether you're taking meds or not.

I try to think of SSRIs as just one of dozens of tools that need to be in the tool box for combating depression.





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