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Re: Which AD treats anhedonia?

Posted by SLS on September 25, 2016, at 8:52:36

In reply to Which AD treats anhedonia?, posted by Hana on August 31, 2016, at 12:45:00

> My anhedonia is caused by SSRIs withdrawal I quit taking them a long time ago (since March this year). I only have social anxiety no depression.
>
> I've been taking Brintellix for a month and a half now. Its effect is mild on SA but unfortunately it did not treat the anhedonia. It actually made it much much worse. Also, B has given me very STRONG sexual side effects. I have ZERO sex drive. The last time I watched porn was like 2 months ago. Now I'm thinking of trying another med, one that treats the f anhedonia. Anyone has suggestions? I don't want to try any APs. My pdoc suggested taking Pristiq.

I just switched from Abilify (aripiprazole) to Rexulti (brexpiprazole). I find that Rexulti is superior such as to improve anhedonia, and increase interest and motivation. Rexulti should be less apt than Abilify to produce akathisia based upon its reduced intrinsic D2 activity. I tried Vraylar (cariprazine). Within a week, I felt terrible. I was expecting a much better response from it compared to Abilify. It is the AP that has the highest ratio of D3/D2 receptors binding, which I thought would improve anhedonia the most.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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