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Re: Dysthymia » KarenRB53

Posted by SLS on September 13, 2016, at 17:14:40

In reply to Dysthymia, posted by KarenRB53 on September 13, 2016, at 16:31:31

Hi.

I made a few suggestions here:

http://www.dr-bob.org/babble/20160819/msgs/1092093.html

I'm sure you know that dysthymia can be particularly stubborn to treat.

I know a woman who has dysthymia and infrequent episodes of major depression. She does reasonably well with Wellbutrin + Abilify. I would like to see her add Lamictal, but she is reluctant to try it again, mainly because monotherapy was not very helpful.

I wonder if intranasal ketamine would hit the target. Another friend of mine has achieved remission using intranasal ketamine. Her depression was rather severe, but she responded partially using a combination of Abilify and Lamictal.

There are so many possibilities. Traditionally, dysthymia has been treated the same way as major depression. Personally, I am not aware of an association between dysthymia and a list of drugs that are most effective to treat it. Quite awhile ago, several people here were treating their dysthymia with a drug called amisulpiride (Solian) that is available in Europe. Early studies showed that low dosages (25-100 mg/day) were tailored for dysthymia, while higher dosages were necessary to treat schizophrenia.

Wellbutrin + Lamictal + Abilify?

I don't like piling up drugs. But, you gotta do what you gotta do. Since no one drug acts on all of the targeted biological sites necessary to produce a therapeutic response, one needs to use multiple agents.

Out of curiosity, what are some of the treatments you have tried so far?


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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poster:SLS thread:1092095
URL: http://www.dr-bob.org/babble/20160819/msgs/1092097.html