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Measuring Drugs Activity at Receptors

Posted by Hello321 on July 1, 2016, at 10:30:25

Im wondering about how strongly meds bind to certain receptors. I dont know if someone on psychobabble might understand how to read the number values for Pimavanserin and Cyproheptadine with the 5ht2a and 5ht2c receptors listed on their Wikipedia pages:

https://en.wikipedia.org/wiki/Cyproheptadine#Overdose

https://en.wikipedia.org/wiki/Pimavanserin

And is there any way to tell which has a stronger effect on the 2a and 2c reveptors at the doses given?

It does say on the Pimavanserin page that its lower number indicated for the 2c receptor means it has lower affinity comoared to the 2a receptor that it shows a higher number for. But that goes against what ive read, that the lower numbers mean theyre actually stronger at those receptors.


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poster:Hello321 thread:1090060
URL: http://www.dr-bob.org/babble/20160609/msgs/1090060.html