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Re: SLS et al.....Lamictal (again!!)

Posted by SLS on April 23, 2016, at 15:45:01

In reply to Re: SLS et al.....Lamictal (again!!), posted by Tabitha on April 20, 2016, at 14:47:04

> > Thank you folks for your previous responses.
> >
> > I have found taking the Lamictal once daily better than twice. I am only started on the 25mg dose. (Was doing 12.5 x 2 daily but not feeling much)Twice daily on 25mg and I get moody and angry and tense.
>
> Hi, Jay. I was told to take 1 per day, and that dosage timing didn't matter. I've been taking it at bedtime, which is what I usually do unless I notice insomnia from a med.
>
> I never tried twice per day dosage. The half-life is 29 hours, so that suggests to me that it's not important to dose multiple times per day like you might need to do with a shorter-acting med.
>
> I'm on 150mg now, but pdoc had me titrate up 25mg every 2 weeks to help avoid the risk of the rash.

There is Lamictal XR. I imagine the drug company felt the need to produce an extended-release formulation for some reason. My personal experience with Lamictal is that I cannot go 30 hours without relapsing. I need to dose other drugs 3x a day, so splitting the dose is no big deal to me. I like to keep blood levels as steady as possible.

Remember - with anticonvulsants, a small difference in blood levels can mean the difference between response and non-response. I think that's why changing from the GSK name brand to the Teva generic caused me to deteriorate.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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poster:SLS thread:1088267
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