Posted by linkadge on March 26, 2016, at 17:40:53
In reply to amitriptyline and apathy?, posted by B2chica on March 26, 2016, at 12:06:23
Amitriptyline does have sedative qualities which can reduce over time. You build some tolerance to the antihistamine effect.
I wouldn't start with anymore than 10mg for a week.
Has the apathy replaced anything else? Is sleep and/or anxiety better? I have noticed that occasionally, when an antidepressant starts working, anxiety and insomnia can be replaced by initial apathy.
I got terribly apathy once starting citalopram, but reducing the dose and giving it time led to a significant response.
I take remeron and it can cause sluggishness and apathy for the first part of the day. I take strong coffee + vitamin D + vitamin b12 to help offset this.
You may get additional sedation with amitriptyline + the sedative. You may need to reduce the sedative to some extent.
If you give it a few weeks, the TCAs are notorious for producing higher rates of remission. Depending on the dose you are taking, a higher dose may actually reduce apathy more.
Linkadge
poster:linkadge
thread:1087573
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