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Parnate insomnia: please help.

Posted by Axmann on January 31, 2016, at 5:46:37

History: 24-year-old male with severe ADD-PI, extremely treatment-resistant depression, and lifelong insomnia.

I'm at the end of my second week of my first time trying Parnate. My response to Parnate has been absolutely miraculous: Social skills increased about tenfold, ability to put words together increased, finally feel somewhat happy for the very first time in my life.

-I take 10 mg dextroamphetamine TID for my ADD-PI.
-The first week I took 10 mg Parnate in the morning and 10 mg Parnate at noon.
-The second week I took 20 mg Parnate in the morning, and 10 mg Parnate at noon.

There's one huge, GIGANTIC, severe roadblock to happiness: the insomnia with Parnate.

I have had insomnia my entire life, so I am not new to sleeping problems. However, something was always able to put me to sleep if needed, and I would always catch up with quite a few hours after a restless night before.

Then came Parnate. The insomnia I get with Parnate is so outrageous and extreme I honestly don't know how to proceed.

On my worst night, (keep in mind this is idiotic and dangerous, so please *DO NOT* attempt it), a sleep cocktail consisting of trazodone, Lunesta, 7.5 mg mirtazapine, Rozerem and suvorexant (Belsomra) put me out for a whole... 2.5 hours. I was absolutely floored. Before Parnate, 7.5 mg mirtazapine alone was my never-lets-me-down sleep med, which would knock me out for 16-17 hours on those days I really needed saving.

It's definitely the Parnate, not the dextroamp. I slept like a baby with only Lunesta when I was taking 75 mg Effexor XR and 30 mg Adderall IR daily. The stimulant med is absolutely non-negotiable; without it, functioning is impossible. I have given Focalin, Concerta, and Strattera fair trials which were unsuccessful.

I am at wit's end. What do I do? I don't want to give up on the one antidepressant that has given me my life back, but without sleep, this is not physically sustainable.

Would cutting back to 20 mg daily help? Taking the dose all at once in the morning? Higher dose of trazodone at night? Would switching to Nardil help?

I am not (nor have I ever been) suicidal, but I am desperate to be happy. Please help.


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poster:Axmann thread:1085832
URL: http://www.dr-bob.org/babble/20160131/msgs/1085832.html