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Re: My new cocktail » former poster

Posted by SLS on November 13, 2015, at 20:37:51

In reply to My new cocktail, posted by former poster on November 13, 2015, at 18:32:49

> Emsam 6mg q.d.
> Fluvoxamine 75mg. b.i.d.
> Clonazepam 1mg b.i.d.
>
> Comments appreciated.

I can't believe your doctor has you taking Emsam and fluvoxamine ocncurrently. He is either the smartest doctor or the dumbest. Either he is very sure that the 6 mg/24 of Emsam is safe while higher dosages are not, or else you are taking an incredibly dangerous combination. There are few more dangerous combinations of psychotropics than adding a serotonin reuptake inhibitor to a MAOI. Emsam is not specific for MAO-B, it is only selective. It loses its selectivity at higher dosages.

You should become familiar with the symptoms of serotonin syndrome. If you develop any of them, you should immediately stop both drugs, not just one, and contact your doctor.

Please refer to several sources of symptom descriptions. Most are not complete.

You really should have someone watch you, as you might become incoherent and incapacitated early during an acute reaction. Monitoring your body temperature for elevation is a good idea. Many fatalities are due to hyperpyrexia.

I imagine it is possible that your doctor has taken this all into consideration. I can't really know. If he knows what he's doing, I apologize for alarming you.

Please see the end of this post.

--------------------------------------------

Here's one list of symptoms of serotonin syndrome:

Mental status changes
Confusion; incoherence (51%)
Agitation (34%)
Hypomania (21%)
Anxiety (15%)
Coma (29%)

Cardiovascular
Sinus tachycardia (36%)
Hypertension (35%)
Hypotension (15%)

Gastrointestinal
Nausea (23%)
Diarrhea (8%)
Abdominal pain (4%)
Salivation (2%)

Motor Abnormalities
Myoclonus (58%)
Hyperreflexia (52%)
Muscle rigidity (51%)
Restlessness (48%)
Tremor (43%)
Ataxia/incoordination (40%)
Shivering (26%)
Nystagmus (15%)
Seizures (12%)

Other
Diaphoresis (45%)
Unreactive pupils (20%)
Tachypnea (26%)
Hyperpyrexia (45%)

--------------------------------------------

http://www.emsam.com/

"Who should not use EMSAM?

Using EMSAM with certain antidepressants and certain pain, cold and cough symptom medicines may cause a potentially life-threatening problem called serotonin syndrome (See What are the possible side effects of EMSAM?).

Do not use EMSAM if you:

take certain medicines including: selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine, sertraline, or paroxetine; serotonin and norepinephrine reuptake inhibitors (SNRI) such as venlafaxine or duloxetine; clomipramine or imipramine... "

--------------------------------------------

Be careful.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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