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Re: Akathisia? Restless Leg Syndrome? Need Some Advice » hello123

Posted by SLS on July 4, 2015, at 7:58:38

In reply to Re: Akathisia? Restless Leg Syndrome? Need Some Advice, posted by hello123 on July 3, 2015, at 21:05:04

> ive not even felt like typing on babble the past few days. my stomach has been feeling ptetty bad.

Sorry to hear that.

> but, for myself, ive experienced a severe decrease in my ability to experience the emotions that make up life.

Unfortunately, that doesn't sound unreasonable. Did the drug produce these things while you were taking it? For how long did you take a SRI before these persistent effects emerged?

> since taking effexor in 2006 my hair has fallen out faster. its not really noticeable but i do miss my hair looking fuller.

Had your hair been falling out prior to Effexor? I don't think you can do much for male-pattern baldness. However, zinc and small amounts of selenium can help in other situations.

> also, because of effexor, some of my facial muscles tense up on their own.

Any bruxism?

> of i straim my muscles even a tiny bit, i feel shaky and more emotionally disconnected afterwards.

This, I've never heard of. It must be scary and frustrating.

> what bit of emotions i have are very sensititive to foods. as soon as i swallow something like chocolate, meat, bread etc... it has its effect.

For me, carbohydrates produce exaggerated fatigue, heart palpitations, and perhaps somewhat flatter affect. This began in the mid-1980s after being on Parnate + desipramine. It hasn't dissipated, regardless of what drugs I am taking. I can't comment on the persistence of these phenomena, though, since I haven't been drug-free but for a few weeks here and there.

> ive never, ever heard of something like this, but this is what im experiencing. i could even yell you the difference between white bread thats been fortified with B Vitamins, and white bread that hasnt been.

> i have very low energy. i vget irritable about some things easily.and my mood is very low. music sounds pretty empty. i no longer get "closed eye visuals". my imagination and ability to laugh are very weak. and just anything that is pleasurable is often too much for me to handle. leaving me feeling completely drained, mentally and physically in a way that i couldnt imagine before my experience with medications.

These sound like common symptoms of depression. Depression itself tends to get worse with time. It would be hard to parse the symptoms of the illness versus persistent drug adverse effects.

What about apathy? Sexual function / sensation? I have heard of these things persisting after SRI discontinuation.

> the worst meds for me were adderall, mirapex and effexor.

I don't like the idea of using Mirapex for depression. It must wreak havoc dopamine receptors.

> i had encephalitis in 2001 that resulted in a 5 day coma, so that could have something to do with why i react so badly to meds with permanent effects on me.

I have no knowledge to share in this area.

> but i dont know the criteria for one to react to mefs like i do. but one example of psych meds permanently altering the brain is when they stop working for someone, and never work again.

Yup.

> a couple of weeks ago i was reading revirws on buspar, on askapatient.com i think. and came across a guys revirw describing how buspar worked great for a certain amount of time. and then one day during the time he was on buspar, out of nowhere his anxiety became much worse than he had ever experienced.

It is often overlooked that Buspar has a major metabolite called 1-PP. This substance is a NE alpha-2 receptor antagonist. As such, it can worsen anxiety in some people. However, I don't know if this effect can be latent or have a tendency to persist beyond drug discontinuation.

Medical treatments for many ailments are not without risks. Unfortunately, the phenomena you list are not well-established in the medical community as risks for taking antidepressants. Hopefully, these things will be mitigated for you once you find an effective treatment for your depression.

It would be interesting to see how you would do with a regimen of Abilify, Lamictal, and possibly Wellbutrin. It would be nice to avoid a SRI if possible.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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