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Re: SSRI + Dexedrine, dangerous bc serotonin syndrome?

Posted by tom2228 on May 4, 2015, at 9:03:01

In reply to Re: SSRI + Dexedrine, dangerous bc serotonin syndrome?, posted by kilo8 on May 3, 2015, at 22:47:42

I wouldn't worry about it, at all. For a while I was on an MAOI (Marplan) + Desoxyn (which is more serotonergic than Dexedrine) AND a tricyclic (desipramine). I am still on the same combination except with Vyvanse instead of the Desoxyn, and I've never had a problem. I've been on Dexedrine + SSRI before as well. Many people respond to both drugs better when in combination and each diagnosis is attended to. The risk of serotonin syndrome with this combination is more of a rare theoretical concern that rarely, rarely pans out in the real world. Serotonin syndrome typically occurs only with the combination of an MAOI + an SSRI or a drug like MDMA.

And I agree about the Prozac, best to avoid that as the amphetamine will build up in your system and can change your dose as well as a whole host of other problems. I wanted to pull my hair out after a month of Prozac + Adderall. Same goes for amphetamines with Wellbutrin, although some people do just fine. Best to avoid the trouble IMO and stick to SSRIs besides Prozac and Paxil.




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