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Re: Has anyone tried Strattera? » fido

Posted by Robert_Burton_1621 on March 2, 2015, at 0:59:14

In reply to Re: Has anyone tried Strattera?, posted by fido on March 1, 2015, at 17:59:26

> hi, but if wellbutrin 300mg didnt work for me then why should strattera work?

As Ed said, they do not have the same mechanisms of action. It would be interesting to know Ed's view about the efficacy of buproprion: it is not prescribed here in Australia except off-label. Gillman opines that buproprion is "is not a clinically significant reuptake inhibitor for either noradrenaline or 5-hydroxytryptamine. It is a weak dopamine reuptake inhibitor; weaker in vitro than sertraline (which is called a selective serotonin reuptake inhibitor). It may possibly have other pro-dopaminergic activity."

See: http://www.psychotropical.com/bupropion

> also, what if strattera makes ocd or anxiety worse?

If that is a possibility, and you notice it, if you are on dual-therapy with an SSRI at the same time, then one option would be to raise the dosage of the SSRI relative to the atomoxetine.



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