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Re: SSRI withdrawal symptoms really scare me! » fido

Posted by Robert_Burton_1621 on March 1, 2015, at 7:17:28

In reply to Re: SSRI withdrawal symptoms really scare me!, posted by fido on February 28, 2015, at 12:18:16

>Hello, no I havent tried prozac.
I dont really know what would be best now.
I mean should I try using prozac only to get rid of the symptoms? or should I try prozac as antidepressant and go really high?>

These are, of course, questions for you and your doctor, but I don't see any obvious advantage to you in going on a therapeutic dosage of fluoxetine given that you have already tried an SSRI unsuccessfully.

I think that if the discontinuation symptoms are really bothering you, using a low dosage of prozac should help considerably. You could start straight away.

Alternatively, have you tried titrating down the cymbalta more slowly?

> I thought also about giving aurorix a chance. Maybe that could work.>

From what I hear from psychopharmacologists, moclobemide is not an effective medication. You might wish to pose that question separately on the forum. I tried aurorix very early on and it did absolutely nothing. In no sense is it comparable clinically to the irreversible MAOIs.

> It's like with my symptoms (depression,ocd,anxiety,adhd) it's impossible to find a combo which is safe and treats all symptoms. :( >

Impossible? Have you reached this conclusion through experience or were you advised to this effect by your doctor?

The OCD and anxiety may best be addressed by taking potent medication which acts primarily on serotonin, and the ADHD - if you cannot take or are not interested in taking Ritalin - may, as a second choice, be treatable by medication which inhibits the reuptake of noradrenalin.

Cymbalta and effexor do both of these things, but the problem with them is that their relative potencies as between serotonin and noradrenaline reuptake inhibition are fixed: you can't fiddle around in view of your response to them by increasing the effect of serotonin vis-a-vis noradrenaline and vice versa.

One solution to this fixed-potency issue is to combine two drugs whose potencies or action you *can* modify independently: an SSRI with a noradrenaline reuptake inhibitor, for instance.

The SSRI sertraline (zoloft) and the TCA nortriptyline combine very well. See, for instance: http://www.psychotropical.com/anti-depressants/general-intro-4

If you went straight on zoloft and nortriptyline, your discontinuaton symptoms would also be significantly, perhaps completely, mollified.

> I feel really lost with all my questions and decisions to make. My pdoc cannot help me with this. I see him only every 8 weeks and then we have like 10 minutes to talk, it's WAY too little time.>

That is totally inadequate time. I am sorry to hear you're restricted in this way. What country are you from?


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