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Re: sales of psychotropic drugs » stan_the_man70

Posted by Robert_Burton_1621 on February 27, 2015, at 15:00:17

In reply to sales of psychotropic drugs » ed_uk2010, posted by stan_the_man70 on February 27, 2015, at 8:21:49

> largest increase: Wellbutrin 30%
> Amphetamine salts 29%
>
> largest decrease: pristiq 21%
> ------------quote reference
> http://psychcentral.com/lib/top-25-psychiatric-medication-prescriptions-for-2013/00019543
> ------------quote reference
>

Very interesting, stan. I thought it might be additionally relevant to examine the cost per strength (which does not necessarily equate with cost per minimum or average therapeutic unit) of anti-depressants. The below list is adapted from Schatzberg (et al), "Manual of Clinical Pychopharmacology," 7th Ed, Amercian Psychiatric Publishing, 2010, pp 669 - 672.

The data is a bit dated now, but still worth looking at. Comparing the relative costs per unit of the new agents with the older agents (TCAs, MAOIs) might be revealing.

There is some data included on comparative cost of generic and brand versions of medications, as well as the number of units per packet a particular medication is routinely sold in.

(I've tried to tabulate this data a number of times, but when I submit my message the format reverts to the untabulate version).

Strength (mg) / Cost per 100

*ANTIDEPRESSANTS*

amitriptyline 25 / 36
amoxapine 25 / 62
bupropion (generic) 100 / 96
bupropion sustained release
(generic) 100 / 169
bupropion extended release
(generic) 150 / 152 (per 30)
bupropion (Wellbutrin) 100 / 338
bupropion sustained release
(Wellbutrin SR) 100 / 209 (per 60)
bupropion extended release
(Wellbutrin XL) 150 / 194 (per 30)
citalopram (Celexa) 20 / 372
clomipramine 50 / 106
desipramine 25 / 116
desvenlafaxine (Pristiq) 100 / 129 (per 30)
duloxetine (Cymbalta) 60 / 480
doxepin 25 / 44
escitalopram (Lexapro) 20 / 338
fluoxetine (Prozac) 20 / 630
fluoxetine delayed release
(Prozac Weekly) 90 / 130 (per 4)
fluvoxamine 50 / 257
imipramine 25 / 72
mirtazapine (Remeron) 30 / 126 (per 30)
nefazodone 100 / 92 (per 60)
nortriptyline 25 / 80
paroxetine (generic) 20 / 81 (per 30)
paroxetine (Paxil) 20 / 116 (per 30)
paroxetine controlled release
(Paxil CR) 25 / 120 (per 30)
phenelzine (Nardil) 15 / 53 (per 60)
protriptyline (generic) 10 / 307
protriptyline (Vivactil) 10 / 379
sertraline (generic) 50 / 285
sertraline (Zoloft) 50 / 302
tranylcypromine (Parnate) 10 / 153
trazodone 50 / 57
trimipramine (Surmontil) 25 / 226
venlafaxine (generic) 37.5 / 200 (per 100)
venlafaxine (Effexor) 37.5 / 148 (per 60)
venlafaxine sustained release
(Effexor XR) 37.5 / 382 (per 90)

*ANTIPSYCHOTICS*

aripiprazole (Abilify) 15 / 485 (per 30)
aripiprazole ODT (Abilify Oral
Disintegrating Tabs) 15 / 577 (per 30)
chlorpromazine 100 / 81
clozapine (generic) 25 / 136
100 / 314
clozapine (Clozaril) 25 / 261
100 / 676
fluphenazine decanoate 25 mg/mL / 16 (per 5-mL)
haloperidol 5 / 78
haloperidol decanoate 100 mg/mL / 30 (per 5-mL)
loxapine 10 / 127
olanzapine (Zyprexa) 5 / 311 (per 30)
10 / 468 (per 30)
olanzapine (Zydis) 5 / 346 (per 30)
10 / 503 (per 30)
perphenazine 8 / 137
pimozide (Orap) 2 / 162
quetiapine (Seroquel) 200 / 949
quetiapine extended release
(Seroquel XR) 200 / 515 (per 60)
risperidone (generic) 2 / 456 (per 60)
3 / 536 (per 60)
risperidone (Risperdal) 2 / 535 (per 60)
3 / 628 (per 60)
risperidone (Risperdal M-Tab) 2 / 279 (per 28)
risperidone ODT (generic) 2 / 263 (per 28)
risperidone (Risperdal Consta) 25 / 296 (per syringe)
37.5 / 445 (per syringe)
ziprasidone (Geodon) 60 / 543 (per 60)
80 / 543 (per 60)

*MOOD STABILIZERS*

carbamazepine (Tegretol) 200 / 34
carbamazepine extended release
(Tegretol XR) 200 / 100
divalproex (generic) 500 / 325
divalproex (Depakote) 500 / 385
divalproex extended release
(generic) 500 / 295 (per 100)
divalproex extended release
(Depakote ER) 500 / 334
gabapentin (generic) 400 / 160
gabapentin (Neurontin) 400 / 230
lamotrigine (generic) 100 / 475 (per 100)
lamotrigine (Lamictal) 100 / 582
lamotrigine extended release
(Lamictal XR) 100 / 328 (per 30)
lithium carbonate 300 / 19
lithium carbonate ER (generic) 300 / 47
450 / 53 (per 100)
lithium carbonate ER
(Lithobid) 300 / 218
topiramate (generic) 100 / 418 (per 60)
topiramate (Topamax) 100 / 464 (per 60)

Note: "Cost is reported as the average wholesale price (AWP) based on AmerisourceBergen Drug Distribution, 2009. If a generic drug is available from more than one manufacturer, at least three prices were averaged to obtain an AWP for the drug." (p. 672)



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