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Drugs in development - for depression topdog

Posted by ed_uk2010 on February 16, 2015, at 13:00:24

In reply to Re: Medical conditions know to cause depression!, posted by topdog on February 16, 2015, at 11:27:14

> Thank you so much for such a comprehensive and detailed reply, it is a big help for me on choosing the tests!

That's good to know!

>Have you heard anything positive about ketamine or its analogues under development?

Drugs acting on the same receptor are highly promising, especially rapastinel (glyx13) and NRX-1074. CERC-301 is a related drug also in development.

LY2456302, a kappa antagonist, is being developed as a possible antidepressant.

>I tried Ketamine on my own IM and it made me feel really good until i started abusing it and the experiment went wrong.

I don't think self-medication with ketamine is ever likely to end well!

>Do you think that the actual antidepressant effect can be felt from Ketamine (like for a week after the injections) when on nardil, asking because nardil can be euphoric too and it may be hard to tell the difference- is it the nardil or the ketamine?

Ketamine's euphoric effects are short-lived. Some people, but not all, do experience a reduction in depressive symptoms a week later.




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