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Re: AAPs are not mood stabilizers » herpills

Posted by SLS on November 8, 2014, at 7:01:53

In reply to Re: AAPs are not mood stabilizers » phidippus, posted by herpills on November 7, 2014, at 8:02:42

> > >Long term seroquel, for instance, compares favorably to lithium for bipolar I.
> >
> > I've never seen a bipolar person do well on Seroquel alone. Those who do well on Seroquel also take a mood stabilizer.
> >
> > Eric
>
> I've noticed a lot of the atypicals have maintenance indications but only if combined with Depakote or Lithium. But why not Lamictal?

In my experience, Lamictal demonstrates little, if any antimanic or prophylactic (mood stabilizer) effects. It may, however, help to suppress ultra rapid cycling when combined with lirhium valproate, or an atypical neuroleptic. It can take as long as six months for treatment to penetrate the cycle. The addition of lamotrigine works better when mania is not evident when first administered.


- Scott

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"Anticonvulsants are not a class when treating mania. While valproate and carbamazepine are significantly more effective than placebo, gabapentin, topiramate, and lamotrigine are not."

http://www.ncbi.nlm.nih.gov/pubmed/20015083

-----------------------------------------

"Lamotrigine added to valproate successfully treated a case of ultra-rapid cycling bipolar disorder"

http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1819.2007.01624.x/pdf

-----------------------------------------


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I dream of things that never were and ask why not.

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