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Re: 2 antipsychotics... » Christ_empowered

Posted by SLS on August 22, 2014, at 14:51:38

In reply to 2 antipsychotics..., posted by Christ_empowered on August 22, 2014, at 12:03:03

> ..sometimes, I take 2-6mgs Risperdal at night on top of my 30 Abilify. My shrink seems unconcerned. Then again..he's public health. APs are apparently ALWAYS the answer!
>
> What's the safety like? Would I be better off with one AP at a higher dose, like Seroquel XR or something? Are some combos better than others?

A friend of mine with schizoaffective disorder did not do well until Saphris (asenapine) was added to the Navane (thiothixene) she has been taking. Of course, the question remains as to whether or not the Navane is still necessary, but I don't think it makes sense for her to experiment at this point. She now has a job and is going to college. She experiences no side effects.

Antipsychotics are far from being identical to each other. They can differ greatly in their properties beyond D2 antagonism. Perhaps you need all of the mechanisms that can only be found in the complementary effects of two antipsychotics taken at the same time.

What are your major concerns regarding the taking of multiple antipsychotics? What evidence have you encountered that would lead you to have these concerns?

You might want to experiment by trialing different antipsychotics by adding them one at a time to the Abilify you are taking. By continuing the Abilify, you will maintain the therapeutic effect and stability it offers you. If one of the antipsychotics added produces robust improvements, you should probably continue taking both drugs at the same time for awhile, and then attempt to gradually discontinue the Abilify. If you deteriorate upon the discontinuation of Abilify, then I guess you will have no better choice than to commit to taking multiple antipsychotics - at least until medical science discovers another treatment that would serve you better.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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