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Re: at 3+ weeks

Posted by sk85 on June 2, 2014, at 15:34:47

In reply to Brintellix seems to deliver what it promises, posted by sk85 on May 21, 2014, at 13:43:48

To conclude my vortioxetine trial so far:

Pros:
-cognitive performance quite much improved
-no insomnia (I get that with SSRIs)
-no sexual SEs
-lowered performance and general anxiety
-no changes in appetite

Neutral:
-slight irritability

Cons:
-unimpressive antidepressant effect
-expensive
-again anhedonic (as mentioned above may have nothing to do with Brintellix)

So overall I'm feeling like I need to increase the dose (very expensive idea) or augment with something to help with mood. Before Brintellix I had ravingly impressive AD effects with sertaline+pramipexole but became completely insomniac on it (also check out: http://www.ncbi.nlm.nih.gov/pubmed/16963794). I might consider trying this time vortioxetine and prami.

I also think I need to give this current dose still few more weeks, at least until 6 weeks. I also suspect I still might have some unaddressed bipolar symptoms that I'm going to take up with my pdoc next meeting. It's really difficult to pinpoint a mild bipolar case.


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poster:sk85 thread:1065908
URL: http://www.dr-bob.org/babble/20140512/msgs/1066381.html