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Re: replace Abilify with perphenazine? Louisiana Sportsman

Posted by ed_uk2010 on April 15, 2014, at 13:32:44

In reply to Re: replace Abilify with perphenazine?, posted by Louisiana Sportsman on April 14, 2014, at 18:44:54

>....why would she need to assess a smaller dosage if she has already responded to that equipotent dosage of the metabolite? I guess you may have a different opinion and that's OK.

Hi,

Oxcarbazepine isn't a metabolite of carbamazepine, but it is structurally closely related, and appears to have a similar mechanism of action. Carbamazepine is metabolised to carbamazepine-10,11-epoxide. Oxcarbazepine is metabolised to eslicarbazepine.

I understand the reasoning behind suggesting a particular drug, but (most) people are not in a position to tell their doctor to prescribe a specific quantity :)

 

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URL: http://www.dr-bob.org/babble/20140328/msgs/1064267.html