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Re: My experience with tianeptine (Stablon) uncouth

Posted by doxogenic boy on March 27, 2014, at 19:44:10

In reply to Re: My experience with tianeptine (Stablon), posted by uncouth on March 27, 2014, at 13:37:20

> Doxo--
>
> I am very interested in hearing more about your experience with TIaneptine--especially how you got to such a high dose! I am quite interested in this medication and have a stock of it, though am currently trying Nardil. What do you take it for, and what effect does it have on you that you can discern...and how did you come to such a high dose? Did your doctor suggest it based on his experience, or was 37.5 simply ineffective.

The reason why I started using tianeptine in combination with SSRI/TCA is that I found a case report in a German journal, a patient who had treatment resistant depression, who reached remission with a combination of sertraline, amitriptyline, carbamazepine and tianeptine.

See the case report in this message:
http://www.dr-bob.org/babble/20140307/msgs/1062040.html

I sent the case report to my psychiatrist, and he agreed to give tianeptine a try. 22th September 2008 I started with tianeptine, and I have used it continuosly since then. When I added tianeptine at this date, I already used 40 mg escitalopram, 100 mg trimipramine, 300 mg pregabalin, 600 mg quetiapine, 30 mg liothyronine and 1 mg clonazepam. (Later I stopped taking pregabalin and clonazepam, and added agomelatine.)

Here is my dose titration of tianeptine:
22 September 2008: 12,5 mg
23 September 2008: 37,5 mg
16 October 2008: 50 mg
19 January 2009: 75 mg
12 March 2009: 87,5 mg
13 March 2009: 100 mg
5 May 2009: 150 mg
25 October 2009: 300 mg (50 mg tianeptine six times a day)

I found out that if I took 50 mg tianeptine in one dose, I felt calm and inner peace after about one hour. Later on I theorized that if I took 50 mg tianeptine every second hour, I would feel good all the time. I asked my psychiatrist if I could try this, and he agreed. It worked, so from late October 2009, my severe treatment resistant depression, which started in about August 2004, was gone! [I have been depressed before too, most of my life.] I thought of suicide and had extreme levels of anxiety all the time for those five years - a living hell - and all my anxiety disappeared when I started with 300 mg/day.

I my country, the welfare state gives me my medication nearly for free, so I get no financial problems for my combination of six meds.

> I have heard that it becomes very stimulating at higher doses but do not have experience myself.

For me this combination was not stimulating, just inner peace without sedation. The best thing is that it still works, after four and a half years! It probably had been different if I took 300 mg tianeptine monotherapy.

Here is my medication history. I started with meds in 1994:
http://www.dr-bob.org/babble/20090826/msgs/914853.html
http://www.dr-bob.org/babble/20130828/msgs/1050311.html

I wonder how my coctail works neurobiologically, since tianeptine and escitalopram has the opposite effect? And maybe there exist other people out there with TRD who can benefit from my cocktail?

- doxogenic


Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine


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poster:doxogenic boy thread:1063199
URL: http://www.dr-bob.org/babble/20140307/msgs/1063318.html