Posted by tom2228 on March 17, 2014, at 22:29:46
In reply to Re: Anyone prefer TCA to MAOI?, posted by phidippus on March 17, 2014, at 22:13:57
> The one thing about taking a tca over an maoi is you get the flexibility of adding other medications in order to augment your treatment-and sometimes that's necessary to treat depression.
>
Eh, the only meds you truly can't use with MAOIs are SSRIs and clomipramine, impiramine, and amitriptyline.. just about?
But in the sense of being able to encounter a doc who's comfortable with those combinations.. definitely more flexibility without the MAOI.> If your depression is severe as you say, the only TCAs that are going to measure up to Marplan in Imipramine and Clomipramine.
>
I've done some foraging and found that Marplan is a dopamine beta-hydroxylase inhibitor, meaning it inhibits the synthesis of NE from DA hence my theory that NE is what I'm really missing. If I had to go off the Marplan, maybe the restoration of NE functioning would offset part of the severity of my depression? In which sense Marplan is both helping and hurting my depression.> >I only feel like myself on Marplan. I don't know who I am off of it.
>
> You probably are beset with symptoms that your inner self says "why am I feeling this way?"
>
Yeah I just feel screwed, like what happened to me -- I could say it's all the sh*t I've been through with the crystal meth battle but I really thing it all comes down to the bipolar getting much worse in the past few years. And that there's something right yet very wrong with my meds combination that I can't figure out.Perhaps Marplan is my crutch that I relied on during those dark years of drugs and vegging out and Marplan is a return to that sense of security with familiar pain. No lie though, it does help with the depression. I think I'm just personalizing the depression and projecting my feelings on these meds.
> >I am afraid I will lose my self of self.
>
> You will never lose your sense of self, I gaurantee it.
>
Thanks. Just the feeling of my cognitive orientation and how I relate to myself. On Marplan I have the sense that I know what I want to do with my life (to become a psychiatrist) and have this gut feeling that it's right.> >Is there anyone who can reassure me that a TCA might just work better?
>
> A TCA might just work better
>
lol. I f*ck*ng hope, if it comes down to that.
> Eric
poster:tom2228
thread:1062694
URL: http://www.dr-bob.org/babble/20140307/msgs/1062705.html