Posted by Frequentfryer on March 16, 2014, at 20:07:53
Hi All.
I have had bad depression and anxiety most of my life and I find a slightly higher then recomended (but responsible) dose of Baclofen. (Baclofen GABA-B agonist similar to Gabapentin and Pregabalin) gives me 100% remission from my symptoms (Don't get much of an effect from it though unless I am taking my Anti-Depressant which is an irreversible MAOI). It helps heaps with my Extreme social Anxiety. For me it's like the pro social and euphoric effects of Alcohol without the retarded motor function and other side effects. (My friends kind of like it to). The problem is I get a tolerance to it fairly quickly. Then get off the stuff (which is really hard) and try to go without it. (Psychiatrists regrets giving it to me and doesn't think I should take it on and off).
Just wondering if anyone else uses these substances for a mood disorder or general well being, which is their favorite, if they could recommend any other GABAnergics alone or in combination and do if they know if Baclofen, Pregabalin and or Gabapentin would have a cross tolerance.
I am especially interested in Tiagabine if anyone has tried it? Probably less of a tolerance their.
I have read on this board its not to popular but taking it with Parnate at a slightly higher dose.... I dunno it might be worth trying.Regards.
poster:Frequentfryer
thread:1062627
URL: http://www.dr-bob.org/babble/20140307/msgs/1062627.html