Posted by phidippus on March 11, 2014, at 11:49:05
In reply to Re: Phidippus. - I see. My apologies. » phidippus, posted by SLS on March 10, 2014, at 23:54:55
Scott,
> My childhood sucked. It was full of parental physical and emotional abuse - that is, when I wasn't being totally neglected.Has borderline personality disorder ever been discussed as a possible diagnosis for you?
My childhood sucked because of peer abuse and neglect. I had trouble socially well into highschool
>I have been depressed since age 10.
I had mood and behavior issues beginning as early as age 5. In my teens I struggled with depression and impulsive behavior.
>The most severe depression began at age 17
My most severe depressive episode occured in 1999 when I had my first mixed bipolar episode. The depression was acute, had psychotic features, including cotard syndrome (I thought I was dead). On top of the bipolar symptoms I had severe OCD symptoms-persistent thoughts of harming others.
What was your depression like at age 17?
>The symptomatology of my depression is most similar to bipolar depression.
What's strange is that I get my mania, ADHD and OCD under control and all I'm left with is a gnawing depression, which I am only now trying to treat. I feel sad and empty. I feel hopeless. I feel this anxiety like everyrthing is wrong. I feel guilty that I haven't become more successful. I lose interest in things that usually bring me joy. I have difficulty concentrating. I sleep too much or too little. I eat less. I have thoughts of hurting myself.
> Parnate 100 mg/day
I wonder if the Parnate is adequate.
> nortriptyline 150 mg/day
I wonder if you'd have a more robust response to Atomoxetine, which also happens to be an NMDA antagonist.
> Lamictal 200 mg/day
> lithium 450 mg/dayWhat's the point of 450 mg of Lithium? You're probably reaping more side effects than benefits. Why not double the Lamictal and drop the Lithium or vice versa?
> prazosin 25 mg/day
(in theory) raises dopamine (DA) levels in the synaptic cleft in the prefrontal cortex and inhibiting extracellular DA concentrations in the nucleus accumbens
How is this helpful to you?
> minocycline 200 mg/day
What does this do?
> Abilify 10 mg/day
Why not Geodon instead? Geodon has a far more sophisticated mechanism of action.
> This regime is tweaked in that each drug has demonstrated its value by attempting its discontinuation.
How odd. I take medication based on whether it makes me feel better or not, not because I feel worse because I stop taking it.
> Dosages have been optimized by careful titration. Dosages have been pushed and reduced as necessary.
I push my medications to the highest dose then reduce to taste.
Have you tried Rilutek?
>I was never to respond robustly to treatment again.
I think you're on too many drugs. There's gotta be a way to simplify your regimen. I find if I take too many meds, sh*t just gets muddy upstairs.
Why not try Parnate and Desipramine again?
Eric
poster:phidippus
thread:1062167
URL: http://www.dr-bob.org/babble/20140307/msgs/1062270.html