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Re: Abilify+ Antidepressants... » Bob

Posted by SLS on October 23, 2013, at 5:38:17

In reply to Re: Abilify+ Antidepressants... » SLS, posted by Bob on October 22, 2013, at 21:51:08

> > > Hi Scott,
> > >
> > > You take parnate and notriptyline?
> >
> > Parnate 80 mg/day
> > nortriptyline 150 mg/day
> > Lamictal 200 mg/day
> > lithium 450 mg/day
> > prazosin 25 mg/day
> > minocycline 200 mg/day
> >
> > > I had to get off Parnate because I hadn't slept more than 5 hours in a year and a half and I was running out of steam.
> >
> > > Parnate certainly worked well for me,...
> >
> > What sorts of things did you try to treat the insomnia?
> >
> > I refused to let insomnia be the thing to prevent me from taking MAOIs. When necessary, I even took a combination of Halcion and Ativan.
> >
> > > but I think it just worked because sleep deprivation alleviates depression and anxiety.
> >
> > I doubt that this was the reason. Sleep deprivation has an acute effect, but cannot be sustained if used everyday. I doubt it would last even one week. Also, 5 hours is really not enough to produce a sleep deprivation antidepressant effect.
> >
> > > I can't be sure, but I sure would have loved to have tried nortityline when I was on Parnate.
> >
> > Well, then this represents hope. You still have something left to try - if not with this doctor, then perhaps with another.
> >
> >
> > - Scott
>
>
> Scott,
>
> I notice that you have kept the prazosin and minocycline on board for quite awhile now. How do you feel these drugs have contributed to your therapy? Can you attribute specific benefits to each, or is there an overall improvement that is more vague?
>
> Bob


That's a good question. I tried discontinuing minoycline and felt noticeably worse. I tried reducing the dosage of prazosin and felt noticeably worse. What does "noticeably" mean? It does not mean remission, to be sure, but it does make my life easier and more worthwhile living. I am currently increasing my Parnate to 100 mg/day. If it works well, I might try discontinuing the prazosin because it obliterates my sex-drive. I have a feeling that I will end up needing it, though.

I have been taking prazosin for 21 months, and minocycline for 14 months.

The only two people I know who take minocycline for depression began to respond while also being on Abilify and Lamictal. Of course, that might be an unrelated coincidence.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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