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Do antidepressants worsen your depression?

Posted by doxogenic boy on October 22, 2013, at 12:46:02

Hi.

In this thread I would like to hear from those of you who have experienced that long-term use of antidepressants has worsened your depression and/or made you treatment-resistant. Did you feel better before you started with antidepressants?

I am satisfied with my meds, but it seems that there are a lot who dont get better.

There is some research that indicates that antidepressants worsen depression for some antidepressant users.

http://www.ncbi.nlm.nih.gov/pubmed/20728491
Excerpt from abstract above:

Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15;35(7):1593-602.
Epub 2010 Aug 20.
The mechanisms of tolerance in antidepressant action.
Fava GA, Offidani E.
There is increasing awareness that, in some cases, long-term use of antidepressant drugs (AD) may enhance the biochemical vulnerability to depression and worsen its long-term outcome and symptomatic expression, decreasing both the likelihood of subsequent response to pharmacological treatment and the duration of symptom-free periods.
Quote end.

Do you feel antidepressants have had this effect on you? How did they change your condition, and how long had you used antidepressants when your depression worsened?

- doxogenic


Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine


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