Posted by g_g_g_unit on October 4, 2013, at 8:01:11
In reply to Re: still feeling bad on Riluzole » g_g_g_unit, posted by SLS on October 4, 2013, at 6:22:56
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> For me, it seems that a combination of Minocycline + Lamictal has modulated excessive glutamate activity. I also take Abilify.My Minocycline trial was cut short by Riluzole, but I still have a box lying around. I'm not that impressed by the results in OCD, though.
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> I was very disappointed by riluzole. It didn't help at all. However, one cannot deduce from this that glutamate dysfunction is not contributing to depression and anxiety.I know, it's pretty heartbreaking, especially since the data for anxiety/depression seems so promising.
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> Have you ever tried Navane (thiothixine) or Phenergan (promethazine) for your anxiety?To be honest, I get akathisia on tiny doses of AAP, so am not foaming at the mouth to try an older antipsychotic. I can't imagine the subjective effects would be too pleasant either.
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> Prazosin is an interesting choice. Recent studies use 20 - 30 mg/day in divided doses. Despite the use of these higher dosages, one must nonetheless begin treatment using a single 1.0 mg dose given at night and follow up 2.0 - 3.0 mg. Even at this low dosage, temporary dizziness often occurs, so a gradual titration is recommended.
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My GP vetoed the Prazosin idea because of low BP.> Is there any history of trauma?
>Not officially, though the last 5 years of living with an anxiety disorder could be described as traumatic.
I read that you said Prazosin could provide AD benefits in patients with childhood abuse .. my mother is narcissistic and a lot of hurtful recollections surfaced in therapy, though I've never been diagnosed with an official traumatic complex.
poster:g_g_g_unit
thread:1051113
URL: http://www.dr-bob.org/babble/20130930/msgs/1051685.html