Posted by doxogenic boy on September 17, 2013, at 14:33:42
In reply to Re: Interactions Antiepileptics/Antipsychotics » doxogenic boy, posted by SLS on September 17, 2013, at 13:01:08
> Thanks for the valuable information!
You're welcome! I think it should be done much more research into interactions with psychotropic drugs.
I find interesting points about interactions in the article "Potentially hazardous drug interactions with psychotropics":
http://apt.rcpsych.org/content/11/6/440.fullSome quotes from the article:
Most interactions are harmless and of only theoretical interest.
[...]The evidence for many potential interactions is based only on in vitro or animal research, single case reports or small-scale uncontrolled studies
[...]For example, enzyme induction by carbamazepine decreases the effectiveness of tricyclic antidepressants and antipsychotics.
[...]Much research has been carried out into potentially hazardous interactions with psychotropic drugs, yet there is much that remains unknown. The evidence for some potential interactions is based on animal experiments, isolated case reports in which there is doubt about the cause-and-effect relationships, or small-scale volunteer studies that may not reflect the action of, and interaction between, drugs in patients.
End of quotes.
I haven't thought of before that most drug interactions are harmless, and that knowlegde of (some of) the potential hazardous interactions are based on limited evidence.
- doxogenic
Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine
poster:doxogenic boy
thread:1050768
URL: http://www.dr-bob.org/babble/20130828/msgs/1050865.html