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Buspar WITHOUT SSRI, WITH melatonin

Posted by uncouth on May 22, 2013, at 18:02:59

Hi all
haven't posted in a while.
just started buspar last week, in addition to a cocktail (strattera, vyvanse, namenda, gabapentin for sleep) for bipolar 2 depression which is mostly in check, but definite mood swings still and low motivation.

i had never tried buspar before, and sent my doc the buspar melatonin paper that has been mentioned elsewhere on this PB and which i came across a few months ago, and since i was already on melatonin for sleep, and buspar has low side effect profile, we thought it might be worth trying.

i destabilize on SSRIs/ especially cymbalta very quickly, ESPECIALLY in summertime (seasonal bipolar).

started buspar last week at 15mg bid. went up to 30mb bid after a few days. bad deal. i read buspar acts like a totally different drug with and without an SSRI.

we also added it to help with some baseline anxiety / social anxiety stuff. but it felt anti-serotonergic and i've been quite irritable. I backed off and am at 15mg bid.

anyway long story, but would just love to get feedback on what people's experiences with buspar has been, at 15mg or higher bid. what should i expect since im taking it without an SSRI? do you have to taper up? am i right to feel an "antiserotonergic" effect? does it ever have a/d properties on its own?

we'll see how this goes with the trial of 3-5mg melatonin time release at night!




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