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Re: Kat is back (again) schleprock

Posted by SLS on March 7, 2013, at 0:29:57

In reply to Re: Kat is back (again), posted by schleprock on March 6, 2013, at 22:45:42

> > I have bipolar and have never had a true manic episode as in bipolar 1. This is what is so VERY misunderstood about bipolar affective disorders. please go to psycheducation.org and click on the link for mood swings without mania. Research the whole site which is dedicated to mood disorders. I would also suggest purchasing Dr. Phelp's book.
>
> From the "Treatment" chapter:
>
> "What if you are currently on an antidepressant?
>
> If you're doing well, maybe continue it. This is controversial"
>
> Please approach a man like Dr. Phelps with caution.

I haven't read Phelp's work. Could you post a link to the paper you cited?

People with a history of recurrent or chronic severe depression are often best continued on an antidepressant should they be lucky enough to find one that works. This has been demonstrated in longitudinal studies. Donald Kupfer was one of the first to research this. He found that antidepressant discontinuation or dosage reduction resulted in relapse rates that were much higher than the continuation of treatment at the dosage necessary to achieve remission.

It is an unfortunate scenario that someone should discontinue an effective treatment with an antidepressant, only to fail to respond to that drug subsequently upon relapse.


- Scott


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Kupfer DJ, Frank E, Perel JM et al. Five year outcome for maintenance therapies in recurrent depression. Arch Gen Psychiatry 1992; 49: 76973


Frank E, Kupfer DJ, Perel JM et al. Three year outcomes for maintenance therapies of recurrent depression. Arch Gen Psychiatry 1990; 47: 10939


Frank E, Kupfer DJ, Perel JM et al. Comparison of full-dose versus half-dose pharmacotherapy in the maintenance treatment of recurrent depression. J Affect Disord 1993; 27: 13945


----------------------------------------------------

- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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