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Re: Zoloft Anxiety at first? » SLS

Posted by CamW on February 18, 2013, at 21:29:06

In reply to Re: Zoloft Anxiety at first? » CamW, posted by SLS on February 18, 2013, at 21:05:13

Scott - I have found that Paxil (paroxetine), with it's anticholinergic effects to be the most effect med for panic disorder. Unfortunately, the anticholinergic effect causes carbohydrate cravings, with it's resultant weight gain.

As for Lexapro (escitalopram), it is being prescribed quite extensively. While I think that it "may" be a more effective antidepressant than Celexa (citalopram), I would only recommend them being used for mild, "reactive" depressive disorders, unless used in combination with or mood modifiers. I find Lexapro & Celexa to be too "clean" as medications. They selectively bind to the serotonin re-uptake receptor & little else. I find that side effects (like the anticholinergic effects of Paxil), can be useful in treating various psychiatric disorders.

NOTE: The last paragraph is based on my "feelings" & "observations", I have NO scientific literature to back up my claims.

>Interestingly, when used to treat depression, Lexapro often will not produce anxiety until day 14. Thereafter, anxiety can exist for 2 to 7 days before subsiding. Do you have any ideas as to why this might be?

See, this throws out some of my answer in my second post to PrettyLady. There is probably a legitimate explanation & may have to do with secondary binding effects of the other SSRIs. These side effects may mask, or slow down, the turnover of the post-synaptic receptors, but again, I have to proof. This is just speculation.

Forgive me buddy, but I am not the font if knowledge that I once was.
As I once relayed to you in an email; you are one of the few people that I would trust with my life. Your opinions and critiques of my answers are much appreciated.- Cam

P.S. We will again get into some of those deep philosophical discussions regarding what depression really is (in our "opinions", of course). - C.


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