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Re: Zipra/Sulpr link? Scott? ALERT:mention of *S* word » SLS

Posted by Delna on November 17, 2012, at 8:08:39

In reply to Re: Zipra/Sulpr link? Scott? ALERT:mention of *S* word » delna, posted by SLS on November 17, 2012, at 6:43:07

> Abilify and Latuda are good choices according to the most current literature. If you feel that you need an energy boost, I would first establish Abilify, Lamictal, and Wellbutrin, and then consider adding minocycline afterwards.
>
> Sulpiride might poop out because dopamine D2 presynaptic receptors eventually upregulate and reduce the synthesis and release of dopamine, thus reversing the initial increase in DA release.
> Yes, Latuda and Sulpiride both exhibit 5-HT7 receptor blockade.

If Abilify doesn't work, then Latuda makes a good second choice.
>
> -------------------------------------
>
> Effexor: 300 mg/day (Perhaps substitute Cymbalta for pain symptoms)
>
> Wellbutrin: 300-450 mg/day
>
> Lamictal: 200 mg/day
>
> Abilify: 2.0-10.0 mg/day
>
> Ritalin: 40 mg/day (Focalin might be better)
>
> Klonopin: 2.0 mg/day
>
> gabapentin: 900 mg/day
>
> -------------------------------------
>
>
> - Scott


Hi Scott,
thanks a lot for your reply!

You said:
"Yes, Latuda and Sulpiride both exhibit 5-HT7 receptor blockade. "

Did you mean lurasidone and ziprasidone have action at 5HT7? Or Lurasidone & Sulpiride?
I have not seen anything that talks about sulpiride and 5ht7 so if you've read that somewhere, that maybe the answer ! Because I am sure that Ziprasidone has action at 5HT7 and if sulpiride does as well, thats what links them!! Can you please tell me where you read about sulpiride and 5HT7?

Then latuda would be worth a shot. It may really work!

I tried Abilify. It was really uselss.

My doctor wants me to take 400mg minocycline, then add mementine. That also acts on glutamate. Gabapentin is way too sedating. I could only tolerate it whilst on Geodon, when nothing could r oversedate me.

Thanks again,
Your input is so helpful!
D

 

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poster:Delna thread:1031452
URL: http://www.dr-bob.org/babble/20121113/msgs/1031459.html