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Re: PS. what should i do? » phidippus

Posted by SLS on October 3, 2012, at 15:46:14

In reply to Re: PS. what should i do? » b2chica, posted by phidippus on October 3, 2012, at 15:17:20

> There is another problem. You're taking 100 mg of Pristiq , which may be destabilizing your mood.

That's very possible.

> That's a maximum dose.

I wish it weren't.

I think 100 mg/day is too low to set as a maximum dose.

http://www.ncbi.nlm.nih.gov/pubmed/22883315

Also, the original clinical trials went up to 400 mg/day. It is in the best interests of the drug company to recommend the lowest dosage they think they can get away with so as to minimize side effects and make their product more marketable. It's a juggling act.

http://www.ncbi.nlm.nih.gov/pubmed/17917552

Pristiq 50 mg/day made you manic. Would 200 mg/day make you more manic? Perhaps this was an all-or-nothing phenomenon once you reached a threshold dose. If I were depressed and had not responded to Pristiq 100 mg/day, I would sure lobby a doctor to try 200 mg/day. I am all but sure that we will see higher dosages of Pristiq used once clinicians begin to push the envelope. Perhaps 300 mg/day of Pristiq will be used as commonly as is 300 mg/day of Effexor. Wyeth suggested a maximum dose of Effexor as 225 mg/day when it first came out. Now, Wyeth recommends 375 mg/day. Interesting, right?


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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