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Re: Other folks who can't tolerate MAOIs??? » jono_in_adelaide

Posted by ChicagoKat on September 28, 2012, at 21:16:49

In reply to Re: Other folks who can't tolerate MAOIs???, posted by jono_in_adelaide on September 28, 2012, at 18:28:48

> What makes nardil so special is that as well as being an MAO inhibitor, it inhibits the breakdown of GABA, so it can have an almost benzodiazepine like effect on anxiety.
>
> One of its downsides is it is less potent on noradrenalin than some drugs (hence its record of being better in reactive/atypical depression than melancholic/biological depression), hence the addition of nortriptyline - the ultimate combination as it were.
>
> Taking Vitamin B6 along with a daily multi is said to lessen some of Nardils side effects

It was amazing. When I went on my first washout to try an MAOI, I was up to 24mg/day of Ativan by the time the washout was done. Then we started Nardil, and within a week, I no longer needed any Ativan at all. The doc was sending me home and offered to write me a script and I said nope, I don't need it. Amazing, and no benzo withdrawal effects at all. And I think, but I'm not sure, that I fall into that reactive/atypical type of depression, so the less noradrenalin the better. I think that may be why Ritalin made me more anxious. I've thought about it, and since I am feeling better,, and I'm having good results from my therapy, I may just try the lower dose of Nardil on its own, without the addition of Nortryptiline. I know you guys have recommended it, but I am really starting to think that more noradrenaline does not do me any good. We'll see what the pdoc thinks. And I'll be sure to take a multivitamin plus some B6. Thanks so much.
Kat


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