Posted by Novelagent on September 13, 2012, at 15:16:22
In reply to Ad's Take Time To Work (if they do), posted by Phillipa on September 7, 2012, at 12:16:55
ADs take at least 3 months. I saw a doc who would switch me just after 3 weeks to another AD if no changes were seen. Luckily another doc saw me and simply upped my lexapro to 30mg 2 months in. I combined it with selegiline without telling him, 5mg/day along with DLPA.
It's possible the Lexapro made for a sort of lowering of the waters hitting the dam in my brain, along with supportive friends I lived with to role model my behavior around, and the structure I had in going to classes and getting my work done, all helped...
But I also know from day one of taking selegiline and DLPA, just as the hypothesis suggested on this board asserted, I had instant effects. I didn't notice it until 2 weeks into the selegiline, but I hadn't craved sleeping since day 1 of taking it up to then, which was huge for me.
It could have been the synergy of lexapro, but I don't advise combining selegiline with another antidepressant, that can cause a hypertensive crisis or serotonin syndrome.
But I think it is wise to consider emsam (it wasn't available as emsam when I took it) and combine it with DLPA. According to a hypothesis advanced on this board around 2004, DLPA traditionally increases dopamine, but it doesn't build up to anything of a therapeutic benefit because it's constantly being destroyed every few minutes.
Yet selegiline, supposedly, captures the dopamine released by DLPA, allowing it to build up over time, thus explaining why it would yield remission of depression from day one.
I remember smiling in two of my classes on day one of selegiline without noticing it until each of my professors called me out for smiling, curious and assuming it was related to the topic being discussed. Smiling spontaneously was huge for me; my professors likely caught me frowning earlier in the semester, I imagine,or at least not smiling.
> There on the web for all to read but subscribe. Intesting as gee who didn't know? Phillipa