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Re: Nortriptyline x Clomipramine » Resistant

Posted by phidippus on August 21, 2012, at 16:28:39

In reply to Re: Nortriptyline x Clomipramine, posted by Resistant on August 20, 2012, at 22:08:02

Nortriptyline inhibits the reuptake of norepinephrine (noradrenaline) and, to a lesser extent, serotonin with negligible effects on dopamine reuptake. Nortriptyline also has antagonistic effects at a variety of receptors:

Strong: H1
Moderate: 5-HT2, α1-adrenergic, mACh
Weak: 5-HT1[1]

Eric


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