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Re: TO SLS » Jeroen

Posted by SLS on August 16, 2012, at 6:45:24

In reply to TO SLS, posted by Jeroen on August 16, 2012, at 4:32:04

> is it safe for me to take this also? because i had a psychotic reaction to lamictal few years ago

I imagine people will have different reactions to minocycline, as is true with other psychotropics. I know it can have an energizing effect early in treatment. Is this an indicator that it can precipitate psychosis in vulnerable individuals? I can't be sure. However, it can reduce the behavioral effects of amphetamine and methamphetamine. This would suggest to me that minocycline can act to reduce psychosis, not trigger it.

http://www.ncbi.nlm.nih.gov/pubmed/20851278

You are down to so few alternatives, though, that it might be worth the risk to try minocycline. It has been researched more extensively for schizophrenia than it has for depressive disorders (MDD and BD). It is known to improve negative symptoms (apathy, emotional blunting, and social withdrawal) and cognitive function, and is usually administered as an adjunct to antipsychotic drugs. I could not find any reports of minocycline producing psychosis on Medline/Pubmed.

You might be interested in this abstract about Lamictal-induced psychosis:

http://www.ncbi.nlm.nih.gov/pubmed/17485241

Keep in mind that there were only 6 cases of emergent psychosis in the 1400 people treated for epilepsy. Unfortunately, you might be one of those 6.

Also, there is this:

http://www.ncbi.nlm.nih.gov/pubmed/17485241

This study contradicts several others. It reports that Lamictal is not effective for treating schizophrenia.


- Scott


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I dream of things that never were and ask why not.

- George Bernard Shaw

 

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