Posted by SLS on August 15, 2012, at 7:14:43
In reply to Re: Starting minocycline. » SLS, posted by Raisinb on August 15, 2012, at 0:30:57
> Good luck with it, Scott.
Thanks. I appreciate that.
> I'll be interested to hear the results.
I will keep you apprised of my progress. It might take a few weeks, although I have seen it work almost immediately.
Although I am using minocycline as an augmenter, some investigators will undoubtedly design clinical studies using it as monotherapy. Results of such studies might be disappointing, although it does display antidepressant properties in animial models of depression (forced-swim test). Minocycline might best be used in conjunction with noradrenergic antidepressants. It makes desipramine work better in some experiments. It acts similarly with anti-glutamate drugs. Because of this, I like the idea of combining minocycline with nortriptyline and Lamictal, a pro-noradrenergic and a anti-glutamergic drug repectively.
Some see things as they are and ask why.
I dream of things that never were and ask why not.
- George Bernard Shaw